Antibiotic susceptibility pattern of Staphylococcus aureus at Sana'a City, Yemen

Tawfique K AlZubiery1, Aref Alhakemy2

Staphylococcus aureus infection has been alarming mainly due to its resistance to several antibiotics S. aureus resistant is widely recognized to be one of the most important public health interventions of the last decades worldwide. Antibiotic resistance S. aureus in our country of growing concern to pay immediate attention and in urgent need for continuously updating knowledge regarding the prevalence of antibiotics resistance. This study aims to study the susceptibility pattern of S. aureus. Study design: This is cross-sectional study conducted in Sana'a city. Methods: Clinical specimens were collected and subjected for isolation and identification. Out of total 421 bacterial isolates, 95 were identified as S. aureus to the species level. Antibiotic susceptibility pattern for all isolates were examined using standard Kirby-Bauer disk diffusion method. Results: Among 95 S. aureus isolates, 74 ̸ 95 (77.9%) and 21 ̸ 95 (22.1 %) were isolated from outpatients and inpatients respectively were considered for the study. The isolates showed low susceptibility rate toward Azithromycin (96.8%), Penicillin (89.5%) and Lincomycin (87.4%). Present study revealed mild (20%) resistant toward fourth generation Quinolone Moxifloxacin and Nitrofurantoin (26.3%) and moderate resistant against second generation Quinolone Lemefloxacin (37.9%) While, 91.6% of S. aureus isolates were found Linezolid susceptible. Conclusion: Linezolid exhibited high protective against antibiotics resistant S. aureus as compared to other antimicrobial groups.

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aureus, Antibiotic resistance, Yemen